Tranexamic acid is a synthetic derivative of the amino acid lysine. It has been used for decades as a treatment for heavy menstrual bleeding and to prevent excessive blood loss during surgery. Recently, it has gained popularity in the skincare industry for its ability to brighten the skin and reduce hyperpigmentation.
Hyperpigmentation occurs when the skin produces too much melanin, resulting in dark spots or patches on the skin. This can be caused by a number of factors, including sun exposure, hormonal changes, and inflammation. Tranexamic acid works by inhibiting the production of melanin, which can help to reduce the appearance of hyperpigmentation and even out skin tone.
One of the main benefits of tranexamic acid is its ability to improve the appearance of melasma, a condition that causes brown patches on the face, typically as a result of hormonal changes or sun exposure.
In a study published in the Journal of Cosmetic Dermatology, patients with melasma who were treated with tranexamic acid showed a significant reduction in the severity of their hyperpigmentation after just 12 weeks of treatment. The study used a topical formulation of tranexamic acid applied twice daily. The researchers noted that tranexamic acid was well-tolerated by the study participants, with no significant adverse effects reported.
In another study published in the Journal of Drugs in Dermatology, patients with post-inflammatory hyperpigmentation were treated with a topical formulation of tranexamic acid applied twice daily for 8 weeks. The researchers found that the tranexamic acid treatment led to a significant reduction in the appearance of the hyperpigmented areas, with no significant adverse effects reported.
A review article published in the Journal of Dermatological Treatment summarized the available evidence on the use of tranexamic acid for skin brightening. The authors noted that tranexamic acid has been shown to be effective in reducing hyperpigmentation caused by various factors, including melasma, post-inflammatory hyperpigmentation, and sun damage. They also noted that tranexamic acid is generally safe and well-tolerated by most people.
Tranexamic acid has also been shown to be effective in reducing post-inflammatory hyperpigmentation, which can occur as a result of acne or other types of skin irritation. In a study published in the Journal of Drugs in Dermatology, patients with post-inflammatory hyperpigmentation who were treated with a topical formulation of tranexamic acid experienced a significant reduction in the appearance of their hyperpigmentation after just 8 weeks of treatment.
Another benefit of tranexamic acid is that it is safe for all skin types. Unlike some other skin brightening ingredients, such as hydroquinone, which can be irritating for sensitive skin, tranexamic acid is gentle and well-tolerated by most people. It can be used alone or in combination with other skincare ingredients, such as vitamin C or niacinamide, to enhance its brightening effects.
In conclusion, tranexamic acid is a safe and effective ingredient for improving the appearance of hyperpigmentation and brightening the skin. It has been shown to be particularly effective in treating melasma and post-inflammatory hyperpigmentation, and is well-tolerated by most skin types. If you are looking to even out your skin tone and reduce the appearance of dark spots, consider incorporating tranexamic acid into your skincare routine.
For a proven skin brightening cream that contains tranexamic acid, check out our Meladerm Pigment Correction cream. Meladerm contains over 10 skin brightening ingredients that work together to reduce the appearance of dark spots and melasma.